Sex seems like an eternally exciting, rewarding and straightforward act. However, for lot of people and couples the reality is quite different. This article is about erectile dysfunction, a common sexual problem in men with diabetes.
What is ED
ED is known as the unrelenting inability to get or sustain an erection that is satisfactory for sexual activity. Lot of men will experience erectile problems during their lifetime, but if the condition lasts for 3 months or longer, it is clinically defined as ED.
Although ED affects most men at some point in their lives, it is much more common in men with diabetes. Fifty percent of men will experience ED within 10 years of diagnosis of diabetes. Older men with a longer duration of diabetes, poor blood glucose control, or who smoke, have high blood pressure, high cholesterol and heart disease, are at a higher risk.
Diabetes causes cause injury to the walls of the blood vessels, which affects circulation and blood flow to the penis. ED can also be a side effect of drugs that are often prescribed to men with diabetes.
Treating ED
There is a number of fruitful treatments for ED. It is important for couples to be involved in any discussion about choice of treatment.Medications with PDE5 inhibitors like Cialis Generic Tadalafil, Sildenafil Citrate, and Vardenafil help men achieve and maintain an erection. With foreplay from partner, these Medications increase blood flow to the penis, allowing an erection to occur naturally.
Wednesday, April 30, 2008
Friday, April 25, 2008
FDA Approves Tadalafil for the Treatment of ED
United States Food and Drug Administration (FDA) has approved generic Cialis, a new oral PDE5 inhibitor, for the treatment of sexual dysfunction (ED). Cialis was shown to improve sexual dysfunction compared to placebo up to 36 hours following dosing. In lab studies, the ability to have sexual activity was increased in some patients at 30 minutes after having a dosage.
Thus, tadalafil joins Sildenafil and Vardenafil HCI as alternative oral pills, all 3 now approved by the U.S. Food & Drug Administration, for erectile dysfunction.
Cialis is not for everybody. Men taking any form of nitrates (often used to control certain chest pain) should not take tadalafil, as the combination could cause an unsafe drop in blood pressure. Men taking pills called "alpha blockers" (sometimes prescribed for prostate problems or high blood pressure) should not take tadalafil. This combination may also cause a significant reduction in blood pressure.
The safety and efficacy of Cialis was evaluated in twenty two clinical trials in more than 4,000 patients. Cialis was shown to be effective in treating impotance in patients 27 to 87 years old, including patients with other underlying medical symptoms. In 2 of these clinical trials, men had impotance associated with diabetes or following radical prostatectomy for prostate cancer.
In clinical studies, the most common side effects with generic Cialis were headache, upset stomach, backache, and muscle ache. Most men weren't bothered by the side effects enough to stop taking generic Cialis. In placebo controlled Phase III clinical studies, discontinuation rates in patients treated with generic Cialis 10 mg or 20 mg was 3.1%, compared to 1.4% in placebo treated patients. Generic Cialis is not recommended in patients who have suffered a heart attack or stroke within the last six months, or patients who have significantly low blood pressure, uncontrolled high blood pressure, unstable angina, severe liver impairment, or retinitis pigmentosa (a rare eye disorder). Men should discuss their health status with their physicians to ensure that generic Cialis is right for them and that they are healthy enough to engage in sexual activity. Generic Cialis does not protect a man or his partner from STD, including HIV.
Thus, tadalafil joins Sildenafil and Vardenafil HCI as alternative oral pills, all 3 now approved by the U.S. Food & Drug Administration, for erectile dysfunction.
Cialis is not for everybody. Men taking any form of nitrates (often used to control certain chest pain) should not take tadalafil, as the combination could cause an unsafe drop in blood pressure. Men taking pills called "alpha blockers" (sometimes prescribed for prostate problems or high blood pressure) should not take tadalafil. This combination may also cause a significant reduction in blood pressure.
The safety and efficacy of Cialis was evaluated in twenty two clinical trials in more than 4,000 patients. Cialis was shown to be effective in treating impotance in patients 27 to 87 years old, including patients with other underlying medical symptoms. In 2 of these clinical trials, men had impotance associated with diabetes or following radical prostatectomy for prostate cancer.
In clinical studies, the most common side effects with generic Cialis were headache, upset stomach, backache, and muscle ache. Most men weren't bothered by the side effects enough to stop taking generic Cialis. In placebo controlled Phase III clinical studies, discontinuation rates in patients treated with generic Cialis 10 mg or 20 mg was 3.1%, compared to 1.4% in placebo treated patients. Generic Cialis is not recommended in patients who have suffered a heart attack or stroke within the last six months, or patients who have significantly low blood pressure, uncontrolled high blood pressure, unstable angina, severe liver impairment, or retinitis pigmentosa (a rare eye disorder). Men should discuss their health status with their physicians to ensure that generic Cialis is right for them and that they are healthy enough to engage in sexual activity. Generic Cialis does not protect a man or his partner from STD, including HIV.
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